DNA

Alec Jeffreys and the Genetic Fingerprint

Alec Jeffreys and the Genetic Fingerprint

On January 9, 1950, British geneticist Alec Jeffreys was born. In 1984, Jeffreys developed techniques for DNA fingerprinting and DNA profiling which are now used worldwide in forensic science to assist police detective work and to resolve paternity and immigration disputes. Alec Jeffries – Youth and Education Alec John Jeffreys was born into a middle-class family in Oxford, UK, where he spent the first six years of his life until 1956, when the family moved to Luton,…
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Maurice Wilkins and the Riddle of the DNA Structure

Maurice Wilkins and the Riddle of the DNA Structure

On December 15, 1916, New Zealand-born British physicist, molecular biologist, and Nobel Laureate Maurice Wilkins was born. Wilkins’ research contributed to the scientific understanding of phosphorescence, isotope separation, optical microscopy and X-ray diffraction, and to the development of radar. He is best known for his work at King’s College London on the structure of DNA. “It is essential for genetic material to be able to make exact copies of itself; otherwise growth…
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John Randall and the Cavity Magnetron

John Randall and the Cavity Magnetron

On March 23, 1905, British physicist and biophysicist Sir John Randall was born. Randall is credited with radical improvement of the cavity magnetron, an essential component of centimetric wavelength radar, which was one of the keys to the Allied victory in the Second World War. It is also the key component of microwave ovens. He also led the King’s College, London team which worked on the structure of DNA. John Randall –…
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Linus Pauling – From Quantum Chemistry to Molecular Biology

Linus Pauling – From Quantum Chemistry to Molecular Biology

On February 28, 1901, American chemist, biochemist, peace activist, author, educator Linus Pauling was born. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions to the theory of the chemical bond include the concept of orbital hybridisation and the first accurate scale of electronegativities of the elements. New Scientist called him one of the 20 greatest scientists of all time, and as of 2000,…
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How Crick and Watson deciphered the DNA

How Crick and Watson deciphered the DNA

On February 28, 1953,  American molecular biologist James D. Watson and English biophysicist Francis Crick announced to friends that they succeeded to determine the chemical structure of DNA. “When finally interpreted, the genetic messages encoded within our DNA molecules will provide the ultimate answers to the chemical underpinnings of human existence.” – James D. Watson, in [11] DNA and RNA – the Prelude In 1869, the Swiss physician Friedrich Miescher discovered a…
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Oswald Avery and the Avery-McLeod-McCarthy Experiment

Oswald Avery and the Avery-McLeod-McCarthy Experiment

On February 1, 1944, physician and medical researcher Oswald Avery together with his colleagues Colin MacLeod and Maclyn McCarty announced that DNA is the hereditary agent in a virus that would transform a virus from a harmless to a pathogenic version. This study was a key work in modern bacteriology. Prelude – The Griffith Experiment The achievement by the scientists Avery, MacLeod, and McCarty were based on Frederick Griffith’s studies on bacteria,…
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Severo Ochoa and the Biological Systhesis of RNA and DNA

Severo Ochoa and the Biological Systhesis of RNA and DNA

On September 24, 1905, Spanish physicist and biochemist Severo Ochoa de Albornoz was born. Ochoa received the 1959 Nobel Prize in Physiology or Medicine together with Arthur Kornberg for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxyribonucleic acid. Severo Ochoa – Early Years Severo Ochoa was born in Luarca (Asturias), Spain, to Severo Manuel Ochoa, a lawyer and businessman, and his mother Carmen de Albornoz. Ochoa…
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Frederick Sanger and the Structure of Proteins

Frederick Sanger and the Structure of Proteins

On August 13, 1918, British biochemist Frederick Sanger was born. In 1958, he was awarded a Nobel Prize in chemistry “for his work on the structure of proteins, especially that of insulin“. In 1980, Walter Gilbert and Sanger shared half of the chemistry prize “for their contributions concerning the determination of base sequences in nucleic acids“. “Scientific research is one of the most exciting and rewarding of occupations. It is like a…
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