pharmacology

John Jacob Abel and the Endocrine Glands

John Jacob Abel and the Endocrine Glands

On May 19, 1857, American biochemist and pharmacologist John Jacob Abel was born. Abel made important contributions to a modern understanding of the ductless, or endocrine, glands. He extracted a derivative of epinephrine, also known as adrenaline and successfully purified and isolated crystalline insulin. His interest in kidney functions led to his invention of a primitive artificial kidney that was able to remove toxins from the blood of living animals, the precursor…
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William Withering and the Clinical Value of Digitalis

William Withering and the Clinical Value of Digitalis

On March 17, 1741, English botanist, geologist, chemist, physician William Withering was born. From his interest in botany, he paid attention to folk remedies used by herb-gatherers, and discovered digitalis, a very useful drug used to steady and strengthen heart action. “In the year 1775 my opinion was asked concerning a family receipt for the cure of the dropsy. I was told that it had long been kept a secret by an old…
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Nicholas Culpeper and the Complete Herbs of England

Nicholas Culpeper and the Complete Herbs of England

On October 18, 1616, English botanist, herbalist, physician, and astrologer Nicholas Culpeper was born. Culpeper spent the greater part of his life in the English outdoors cataloging hundreds of medicinal herbs. Thus, he is best known for his publication of Complete Herbal (1653), a comprehensive listing of English medicinal herbs and their uses, which still is in print today. “I cannot build my faith upon Author’s words, nor believe a thing because they…
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Paracelsus – a Typical Renaissance Scientist?

Paracelsus – a Typical Renaissance Scientist?

Probably in 1493,  the famous Renaissance physician, botanist, alchemist, astrologer, and general occultist, who called himself Paracelsus — with all testified names that never all occur simultaneously he can also be referred to as Philippus Theophrastus Aureolus Bombast von Hohenheim, was born. “All is interrelated. Heaven and earth, air and water. All are but one thing; not four, not two and not three, but one. Where they are not together, there is only…
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Sir James Black and the Beta Blockers

Sir James Black and the Beta Blockers

On June 14, 1924, British pharmacologist and Nobel Laureate Sir James Whyte Black was born. Black developed propranolol, a beta blocker used for the treatment of heart disease. Black was also responsible for the development of cimetidine, a H2 receptor antagonist, a drug used to treat stomach ulcers. For both developments he was awarded the 1968 Nobel Prize in Medicine. “I call myself a pharmacological toolmaker. ” — Sir James W. Black, as…
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